Title

Production of 17F, 15O and Other Radioisotopes for PET using a 3 MV Electrostatic Tandem Accelerator

Document Type

Conference Proceeding

Publication Date

6-1999

Department

Physics and Astronomy

Abstract

Target systems for the production of positron emitting radioisotopes used for medical research with positron emission tomography (PET) are under development for a 3 MV electrostatic tandem accelerator (NEC 9SDH-2). This machine is intended primarily for the continuous production of short lived tracers labeled with 15O (t1/2=122 s) or 17F (t1/2=65 s) for determining regional cerebral blood flow in humans. Simple gas, liquid, and solid target systems are presented for the production of [15O]H2O (yield at saturation 13 mCi/μA), [17F]F2 (22 mCi/μA), [17F] fluoride (aq.) (12 mCi/μA), [18F] fluoride (aq.) (21 mCi/μA), [13N] in graphite (25 mCi/μA), and [11C]CO2 (2.3 mCi/μA). Current limitations on single window targets for each production are discussed.

Paper presented at the 15th International Conference on the Application of Accelerators in Research and Industry, November 4-7, 1998 in Denton, TX.

Publication Title

AIP Conference Proceeding

DOI

10.1063/1.59303

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