Event Title

Investigating the Reactivity of Citral and Octanal Toward DNA

Location

CSU Ballroom

Start Date

16-4-2013 10:00 AM

End Date

16-4-2013 12:00 PM

Student's Major

Chemistry and Geology

Student's College

Science, Engineering and Technology

Mentor's Name

Danae Quirk Dorr

Mentor's Department

Chemistry and Geology

Mentor's College

Science, Engineering and Technology

Description

Citral and octanal are compounds found in citrus fruits, grasses and perfumes. It has been found that aldehyde groups can react with the nucleotides of DNA and form covalent linkages. Since citral and octanal are aldehydes, they were allowed to react with DNA. This project has been localized around exploring the potential products that form when DNA and its nucleosides 2’-deoxyguanosine and 2’- deoxyadenosine react independently with octanal and citral. The reaction mixtures were analyzed by HPLC and NMR.

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Apr 16th, 10:00 AM Apr 16th, 12:00 PM

Investigating the Reactivity of Citral and Octanal Toward DNA

CSU Ballroom

Citral and octanal are compounds found in citrus fruits, grasses and perfumes. It has been found that aldehyde groups can react with the nucleotides of DNA and form covalent linkages. Since citral and octanal are aldehydes, they were allowed to react with DNA. This project has been localized around exploring the potential products that form when DNA and its nucleosides 2’-deoxyguanosine and 2’- deoxyadenosine react independently with octanal and citral. The reaction mixtures were analyzed by HPLC and NMR.

Recommended Citation

Leeder, Brittany. "Investigating the Reactivity of Citral and Octanal Toward DNA." Undergraduate Research Symposium, Mankato, MN, April 16, 2013.
http://cornerstone.lib.mnsu.edu/urs/2013/poster-session-A/37