Event Title

The Effect of Steroid Hormones on Neuronal Size and Number in Two Brain Regions Important for Reproduction

Location

CSU Ballroom

Start Date

18-4-2016 10:00 AM

End Date

18-4-2016 11:30 AM

Student's Major

Biological Sciences

Student's College

Science, Engineering and Technology

Mentor's Name

Rachel Cohen

Mentor's Department

Biological Sciences

Mentor's College

Science, Engineering and Technology

Description

Steroid hormones, such as testosterone (T) and its metabolites (estradiol, E2, and dihydrotestosterone, DHT), are critical for the production of reproductive behavior. These hormones play a role in neural plasticity, such as changes in neuronal size change and brain region volume. Our study is examining the role of steroid hormones in maintaining the morphology of brain areas involved in reproduction, such as the ventromedial hypothalamus (VMH) and preoptic area (POA). We are using the green anole lizard (Anolis carolinensis) as a model because they are seasonally dimorphic, with more reproductive behaviors and higher steroid hormones in the breeding compared to non-breeding season. We treated our animals with different steroid hormones: T, DHT, E2, and blank capsules as a control. We collected the brains, sectioned the tissue and measured neuron size, number and density in the VMH and POA. We are expecting to find smaller and increased numbers of neurons in the animals treated with steroid hormones compared to the controls. This result would support the idea that steroid hormones are critical for the maintenance of brain areas important for reproduction.

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Apr 18th, 10:00 AM Apr 18th, 11:30 AM

The Effect of Steroid Hormones on Neuronal Size and Number in Two Brain Regions Important for Reproduction

CSU Ballroom

Steroid hormones, such as testosterone (T) and its metabolites (estradiol, E2, and dihydrotestosterone, DHT), are critical for the production of reproductive behavior. These hormones play a role in neural plasticity, such as changes in neuronal size change and brain region volume. Our study is examining the role of steroid hormones in maintaining the morphology of brain areas involved in reproduction, such as the ventromedial hypothalamus (VMH) and preoptic area (POA). We are using the green anole lizard (Anolis carolinensis) as a model because they are seasonally dimorphic, with more reproductive behaviors and higher steroid hormones in the breeding compared to non-breeding season. We treated our animals with different steroid hormones: T, DHT, E2, and blank capsules as a control. We collected the brains, sectioned the tissue and measured neuron size, number and density in the VMH and POA. We are expecting to find smaller and increased numbers of neurons in the animals treated with steroid hormones compared to the controls. This result would support the idea that steroid hormones are critical for the maintenance of brain areas important for reproduction.

Recommended Citation

Son, Jaeyoung. "The Effect of Steroid Hormones on Neuronal Size and Number in Two Brain Regions Important for Reproduction." Undergraduate Research Symposium, Mankato, MN, April 18, 2016.
http://cornerstone.lib.mnsu.edu/urs/2016/poster-session-A/28