Multiple sclerosis is a chronic, neurological, autoimmune condition that is characterized by unpredictable demyelination of the central nervous system. Multiple sclerosis remains one of the most debilitating neurological diseases for young adults, affecting an average of 2.5 per 100,000 people worldwide. The objective of this research was to further assess the efficacy of non-pharmacological treatment methods for symptom management and disease progression for multiple sclerosis. A systemic literature review was conducted using 4 research databases: American Search Premier, Medline, Cochrane, and CINAHL. Studies were included if they addressed nonpharmacological treatment approaches to multiple sclerosis. A total of 21 research articles were used to assess inclusion or exclusion criteria. What the research concluded was that there was not definitive evidence to prove that any non-pharmacological treatment method would guarantee a decrease in disability or increase in overall quality of life for patients with multiple sclerosis. However this body of research did show that non-pharmacological interventions could provide some benefit and none of these non-pharmacological treatment methods were harmful, thus validating the safety and potential benefit to be implemented in practice. Much more research needs to be conducted to look specifically at different nonpharmacological treatment approaches for the management of multiple sclerosis as varying symptoms make it difficult to pinpoint the exact benefit that each nonpharmacological approach may have.


Rhonda Cornell

Date of Degree




Document Type



Master of Science in Nursing (MSN)


School of Nursing


Allied Health and Nursing



Rights Statement

In Copyright