High Yield [18F]F2 Targetry for 19 MeV Protons
Physics and Astronomy
An [18F]F2 target system using the 18O(p,n)18F reaction with 19 MeV protons on [18O]O2 gas has produced reliable end of bombardment yields up to 79 GBq (2.1 Ci) at specific activities up to 850 MBq/μmol. The aluminum body target operates on a two-step activation/recovery irradiation protocol. Up to 63 GBq (1.7 Ci) [18F]F2 has been recovered 35 minutes after gas activation. As much as 7.8 GBq (212 mCi) of the PET radiopharmaceutical L-6-[18F]fluoro-DOPA has been produced using [18F]F2 from this target.
AIP Conference Proceedings
A.D. Roberts, M. Constantinou, S.K. Luthra, B. Mackay, M. Renton, and N. Steel. (1997). High Yield [18F]F2 Targetry for 19 MeV Protons. AIP Conference Proceedings, 392, 1337.
Publisher's Copyright and Source
Copyright © 1997 American Institute of Physics. Proceeding published by the American Institute of Physics in AIP Conference Proceedings, volume 392, page 1337. Available online: http://dx.doi.org/10.1063/1.52440