Title

Production of 17F, 15O and Other Radioisotopes for PET using a 3 MV Electrostatic Tandem Accelerator

Authors

Andrew D. Roberts, Minnesota State University - MankatoFollow
Richard J. Davidson, University of Wisconsin - MadisonFollow
Robert J. Nickles, University of Wisconsin - Madison

Document Type

Conference Proceeding

Publication Date

6-1999

Abstract

Target systems for the production of positron emitting radioisotopes used for medical research with positron emission tomography (PET) are under development for a 3 MV electrostatic tandem accelerator (NEC 9SDH-2). This machine is intended primarily for the continuous production of short lived tracers labeled with 15O (t1/2=122 s) or 17F (t1/2=65 s) for determining regional cerebral blood flow in humans. Simple gas, liquid, and solid target systems are presented for the production of [15O]H2O (yield at saturation 13 mCi/μA), [17F]F2 (22 mCi/μA), [17F] fluoride (aq.) (12 mCi/μA), [18F] fluoride (aq.) (21 mCi/μA), [13N] in graphite (25 mCi/μA), and [11C]CO2 (2.3 mCi/μA). Current limitations on single window targets for each production are discussed.

Paper presented at the 15th International Conference on the Application of Accelerators in Research and Industry, November 4-7, 1998 in Denton, TX.

Department

Physics and Astronomy

Publication Title

AIP Conference Proceeding

Recommended Citation

A.D. Roberts, R.J. Davidson, and R.J. Nickles. Production of 17F, 15O and Other Radioisotopes for PET using a 3 MV Electrostatic Tandem Accelerator. (1999). AIP Conference Proceedings, 475, 1006.

DOI

10.1063/1.59303

Link to Publisher Version (DOI)

http://dx.doi.org/10.1063/1.59303

Publisher's Copyright and Source

Copyright © 1999 American Institute of Physics. Conference proceeding published by the American Institute of Physics in AIP Conference Proceedings, volume 475, 1999, page 1006. Available online: http://dx.doi.org/10.1063/1.59303.