Up to 80% of United States (U.S.) citizens will contract the human papillomavirus (HPV) at some point in their lives. HPV has the ability to cause multiple types of cancer, including cervical, vulvar, vaginal, penile, anal, and oropharyngeal. The most recent HPV vaccine is effective against nine strains of the virus, which account for most cases of cancer and genital warts caused by HPV. Parents are a key component in reaching Healthy People 2030’s goal to have 80% of all adolescents in the U.S. completely vaccinated against HPV. Objective: The purpose of this systematic review was to determine if parental education regarding the implications associated with contracting an HPV infection and the development of cancer and knowledge of the impact of the HPV vaccine on HPV infection rates (and thus cancer prevention) could increase adolescent vaccination initiation and completion rates in the U.S. Results: Research does not strongly support education as a sole intervention to achieve Healthy People 2030’s goal. Findings: Multiple interventions are likely necessary to impact HPV infection and vaccination rates in adolescents, including parental education, policy change, public health campaigns, and public health interventions such as school-based vaccination clinics.


Hans-Peter de Ruiter

Date of Degree




Document Type



Master of Science in Nursing (MSN)


School of Nursing


Allied Health and Nursing


Rights Statement

In Copyright