Title

MAO-B Inhibition Downregulates Striatal Aromatic Amino Acid Decarboxylase (AAAD) Activity in Rhesus Monkeys in Vivo

Authors

Onofre T. DeJesus, University of Wisconsin - Madison
Leo G. Flores, University of Wisconsin - Madison
Dhanabalan Murali, University of Wisconsin - Madison
Andrew D. Roberts, Minnesota State University - MankatoFollow
Steven E. Shelton, University of Wisconsin - Madison
Terrence R. Oakes, University of Wisconsin - Madison
David W. Dick, University of Wisconsin - MadisonFollow
Robert J. Nickles, University of Wisconsin - Madison

Document Type

Conference Abstract

Publication Date

5-2002

Abstract

The goal of this study is to determine the effect of MAO blockade on AAAD activity in non-human primate brain, in vivo, using PET imaging with fluoro-m-tyrosine (FMT), a selective PET imaging agent for assessing AAAD activity.

Paper presented at the 49th Annual Meeting of the Society of Nuclear Medicine, Abstract number 385.

Department

Physics and Astronomy

Publication Title

Journal of Nuclear Medicine

Recommended Citation

O.T. DeJesus, L.G. Flores, D. Murali, A.D. Roberts, S.E. Shelton, T.R. Oakes, D.W. Dick, and R.J. Nickles. (2002). MAO-B Inhibition Downregulates Striatal Aromatic Amino Acid Decarboxylase (AAAD) Activity in Rhesus Monkeys in Vivo. Journal of Nuclear Medicine, 43(5, suppl. abstract book), 107P.

Publisher's Copyright and Source

Copyright © 2002 Society of Nuclear Medicine. Article published by the Society of Nuclear Medicine in Journal of Nuclear Medicine, volume 43, issue number 5 - suppl. abstract book, May 2002, 107P.