Physics and Astronomy Department Publications

Production and Test of 18F Samples in the SNICS Ion Source

K. E. Rehm, Argonne National Laboratory
M. Paul, Hebrew University of Jerusalem
Andrew D. Roberts, Minnesota State University - MankatoFollow
Robert J. Nickles, University of Wisconsin - Madison

Document Type

Abstract

Publication Date

1995

Abstract

For experiments with {sup 18}F beams the output of the SNICS ion source for fluorine ions was investigated. {sup 18}F, which is a well-studied PET isotope, is generated at the medical cyclotron of the University of Wisconsin. Aqueous [{sup 18}F] fluoride ions are produced via the {sup 18}O(p,n){sup 18}F reaction using a 30-{mu}A, 11.4-MeV proton beam bombarding a 95% enriched [{sup 18}O] water target. In order to minimize the {sup 18}O component of the {sup 18}F material the [{sup 18}F] fluoride must be separated from the [{sup 18}O] water. For this purpose the aqueous [{sup 18}F] fluoride solution ({approximately} 0.5-1 ml) is removed from the production target and placed in a glassy carbon vessel. The vessel is heated to 115{degrees}C with He bubbling through the solution, evaporating the water while the {sup 18}F adheres to the vessel walls. When dry, the vessel is filled with 1 ml {sup 18}O-depleted 99.98% [{sup 16}O] water which is again evaporated. After this step is repeated once more the vessel is filled with 1.5 ml [{sup 16}O] water and 200-300 mole of natural KF as carrier material.

Department

Physics and Astronomy

Publication Title

Physics Division Annual Report, April 1, 1994 - March 31, 1995

Recommended Citation

K.E. Rehm, M. Paul, A.D. Roberts, and R.J. Nickles. (1995). Production and Test of 18F Samples in the SNICS Ion Source. In Physics Division Annual Report, April 1, 1994-March 31, 1995, pp. 55-56. Argonne, IL: Argonne National Laboratory. Technical Report ANL--95/14 (TRN:95:007970-0061), for the U.S. Department of Energy, Nuclear Physics Division (contract number W-31-109-ENG-38). OSTI Identifier: 166348.