The Effects of a High Lipid Diet on the Physiological Functions of Mice
Location
CSU
Student's Major
Biological Sciences
Student's College
Science, Engineering and Technology
Mentor's Name
Michael Bentley
Mentor's Department
Biological Sciences
Mentor's College
Science, Engineering and Technology
Description
atly foods are composed of a high amount of lipids and typically are foods that "taste good". The purpose of this study is to investigate the effects of a high lipid diet on Swiss Webster Mice. This study examined whether mice on a high fat diet gain more weight than control mice on a normal diet. One group of 10 mice was fed a high fat diet {Labdiet 5015, 11.4 percent fat) as compared to the other group of 10 mice on a normal diet (Labdiet 5001, 5.5 percent fat). The mice were weighed throughout a 310-day time period. At intervals, the mice were placed in metabolic cages to measure food and water consumption, and urine output. Mice on the high fat diet (53.8 +/- 0.70 grams) were significantly heavier (P<0.0001) than the normal diet mice (42.7 +/- 0.54 grams). In the metabolic cages, the mice on the high fat diet ate significantly less (P<0.02) than the mice on the normal diet. The food consumed per body weight for the mice fed on the high fat diet was 0.056 +/- O.OI, as compared to the mice fed on the normal diet at 0.104 -i-/- 0.02. There were no differences in water consumption or urine output. The results suggest the weight gain was a result of the added lipid content in the high fat diet. Supported by the College of Graduate Studies and Research.
The Effects of a High Lipid Diet on the Physiological Functions of Mice
CSU
atly foods are composed of a high amount of lipids and typically are foods that "taste good". The purpose of this study is to investigate the effects of a high lipid diet on Swiss Webster Mice. This study examined whether mice on a high fat diet gain more weight than control mice on a normal diet. One group of 10 mice was fed a high fat diet {Labdiet 5015, 11.4 percent fat) as compared to the other group of 10 mice on a normal diet (Labdiet 5001, 5.5 percent fat). The mice were weighed throughout a 310-day time period. At intervals, the mice were placed in metabolic cages to measure food and water consumption, and urine output. Mice on the high fat diet (53.8 +/- 0.70 grams) were significantly heavier (P<0.0001) than the normal diet mice (42.7 +/- 0.54 grams). In the metabolic cages, the mice on the high fat diet ate significantly less (P<0.02) than the mice on the normal diet. The food consumed per body weight for the mice fed on the high fat diet was 0.056 +/- O.OI, as compared to the mice fed on the normal diet at 0.104 -i-/- 0.02. There were no differences in water consumption or urine output. The results suggest the weight gain was a result of the added lipid content in the high fat diet. Supported by the College of Graduate Studies and Research.
