Analysis of Potential Chemical Reactivity's Between Selected O-T-C and Commonly Prescribed Drugs
Location
CSU Ballroom
Start Date
21-4-2008 1:00 PM
End Date
21-4-2008 3:00 PM
Student's Major
Chemistry and Geology
Student's College
Science, Engineering and Technology
Mentor's Name
Danae Quirk Dorr
Mentor's Department
Chemistry and Geology
Mentor's College
Science, Engineering and Technology
Description
Potential drug-drug reactions between over-the-counter (OTC) medications and commonly prescribed drugs were the focus of this proposal. Various drugs were classified based upon their chemical structures and reactive sites. These drugs were organized into a table format illustrating the different functional groups present in the drugs' chemical structures. Out of sixty-eight drugs analyzed, six were chosen as the primary focus of this experiment. The six drugs include atenolol, captopril, pseudoephedrine, amantadine, metformin, and acyclovir. The goal of this proposal was to correctly predict which drugs would react when taken concurrently. The six selected drugs were reacted under acidic conditions to represent the stomach environment. The reaction solutions were analyzed appropriately by HPLC and LCMS.
Analysis of Potential Chemical Reactivity's Between Selected O-T-C and Commonly Prescribed Drugs
CSU Ballroom
Potential drug-drug reactions between over-the-counter (OTC) medications and commonly prescribed drugs were the focus of this proposal. Various drugs were classified based upon their chemical structures and reactive sites. These drugs were organized into a table format illustrating the different functional groups present in the drugs' chemical structures. Out of sixty-eight drugs analyzed, six were chosen as the primary focus of this experiment. The six drugs include atenolol, captopril, pseudoephedrine, amantadine, metformin, and acyclovir. The goal of this proposal was to correctly predict which drugs would react when taken concurrently. The six selected drugs were reacted under acidic conditions to represent the stomach environment. The reaction solutions were analyzed appropriately by HPLC and LCMS.
Recommended Citation
Faulks, Lindsey. "Analysis of Potential Chemical Reactivity's Between Selected O-T-C and Commonly Prescribed Drugs." Undergraduate Research Symposium, Mankato, MN, April 21, 2008.
https://cornerstone.lib.mnsu.edu/urs/2008/poster-session-B/25
