Exploring the Potential Reaction Between DNA and 5-HydroxymethyIfurfural
Location
CSU 284
Start Date
27-4-2009 10:00 AM
End Date
27-4-2009 12:00 PM
Student's Major
Biological Sciences
Student's College
Science, Engineering and Technology
Mentor's Name
Danae Quirk Dorr
Mentor's Department
Chemistry and Geology
Mentor's College
Science, Engineering and Technology
Description
5-hydroxymethylfurfiiral (HMF) is a substance that is found in many foods that we consume for example milk-j juice and fruits. The purpose of this project was to explore the possibility that HMF may react with the DNA in our cells. DNA is the hereditary material in organisms. Information in the DNA is stored as a code made up of four chemical bases: Adenine (A), Guanine (G), cytosine (C), and Thymine (T). Previous research has shown that aldehydes can react with DNA. HMF is an aldehyde, if an aldehyde reacts with DNA may interfere with the hereditary material and replication. In this project the reaction between HMF and DNA was analyzed by HPLC.
Exploring the Potential Reaction Between DNA and 5-HydroxymethyIfurfural
CSU 284
5-hydroxymethylfurfiiral (HMF) is a substance that is found in many foods that we consume for example milk-j juice and fruits. The purpose of this project was to explore the possibility that HMF may react with the DNA in our cells. DNA is the hereditary material in organisms. Information in the DNA is stored as a code made up of four chemical bases: Adenine (A), Guanine (G), cytosine (C), and Thymine (T). Previous research has shown that aldehydes can react with DNA. HMF is an aldehyde, if an aldehyde reacts with DNA may interfere with the hereditary material and replication. In this project the reaction between HMF and DNA was analyzed by HPLC.
Recommended Citation
Kobingi, Teddy. "Exploring the Potential Reaction Between DNA and 5-HydroxymethyIfurfural." Undergraduate Research Symposium, Mankato, MN, April 27, 2009.
https://cornerstone.lib.mnsu.edu/urs/2009/oral-session-06/5
