Exploring Reactions Between Substituted-Aromatic Aldehydes and Guanosine
Location
CSU Ballroom
Start Date
11-4-2017 10:00 AM
End Date
11-4-2017 11:30 AM
Student's College
Science, Engineering and Technology
Mentor's Name
Danae Quirk Dorr
Mentor's College
Science, Engineering and Technology
Description
The reactivity of substituted-aromatic aldehydes with guanosine and arginine can help elucidate information about how these chemicals could react within our bodies. The aromatic aldehydes selected in this experiment include o-nitrobenzaldehyde, p-nitrobenzaldehyde, salicylaldehyde, and 5-nitrosalicylaldehyde. Reactivity of each aldehyde was explored through four different reactions: 1) aldehyde alone, 2) aldehyde with guanosine, 3) aldehyde with arginine and 4) aldehyde with guanosine and arginine. In total, sixteen separate reactions were conducted at 50C. d6-Dimethyl sulfoxide was used as the solvent in each reaction. Reaction mixtures were analyzed by proton nuclear magnetic resonance (H1-NMR) and high performance liquid chromatography (HPLC).
Exploring Reactions Between Substituted-Aromatic Aldehydes and Guanosine
CSU Ballroom
The reactivity of substituted-aromatic aldehydes with guanosine and arginine can help elucidate information about how these chemicals could react within our bodies. The aromatic aldehydes selected in this experiment include o-nitrobenzaldehyde, p-nitrobenzaldehyde, salicylaldehyde, and 5-nitrosalicylaldehyde. Reactivity of each aldehyde was explored through four different reactions: 1) aldehyde alone, 2) aldehyde with guanosine, 3) aldehyde with arginine and 4) aldehyde with guanosine and arginine. In total, sixteen separate reactions were conducted at 50C. d6-Dimethyl sulfoxide was used as the solvent in each reaction. Reaction mixtures were analyzed by proton nuclear magnetic resonance (H1-NMR) and high performance liquid chromatography (HPLC).
Recommended Citation
Kim, Dahye. "Exploring Reactions Between Substituted-Aromatic Aldehydes and Guanosine." Undergraduate Research Symposium, Mankato, MN, April 11, 2017.
https://cornerstone.lib.mnsu.edu/urs/2017/poster-session-A/31
