Abstract

Cardiovascular disease (CVD) is a multifactorial disease that involves the interplay of many risk factors. Traditional risk factors as defined by the American Heart Association fail to account for all instances of atherosclerosis and CVD. Only within the last 100 years have infectious diseases gained prominence as potential risk factors for cardiovascular illnesses. Within the last 50 years, Chlamydiae pneumoniae, a pervasive intracellular pathogen, has been implicated in the development of atherosclerosis and CVD. This investigation aimed to clarify the relationship between Chlamydia pneumoniae (C. pneumoniae) and CVD. This task was accomplished through in-depth research within the literature of PubMed, using Koch’s postulates as guidelines to determine the role of C. pneumoniae in cardiovascular disease. Findings from this investigation suggest a causative relationship between C. pneumoniae and CVD. In addition to traditional risk factors, this investigation found C. pneumoniae to be a risk factor in the development of atherosclerosis and ensuing cardiovascular disease.

Advisor

Penny Knoblich

Committee Member

Daniel Toma

Committee Member

Michael Bentley

Date of Degree

2018

Language

english

Document Type

APP

Degree

Master of Science (MS)

Program of Study

Biology

Department

Biological Sciences

College

Science, Engineering and Technology

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Rights Statement

In Copyright