The Influence of Kaolinite on the Fate of Erythromycin in Soil Environments

Location

CSU North Ballroom

Start Date

25-4-2006 10:00 AM

End Date

25-4-2006 12:00 PM

Student's Major

Chemistry and Geology

Student's College

Science, Engineering and Technology

Mentor's Name

Trent Vorlicek

Mentor's Department

Chemistry and Geology

Mentor's College

Science, Engineering and Technology

Description

This project seeks to quantify the loss of erythromycin, a common antibiotic for animals and humans, as well as identify any degradation products caused by the surface of kaolinite, a common clay mineral. Antibiotics are commonly introduced into soil environments by treatment plant effluent and agricultural runoff. The introduction of antibiotics is of particular concern because it may promote microbial resistance. Clay minerals are known to adsorb organic molecules and promote their degradation. In order to gain insight into the nature of the clay/erythromycin interactions, experiments are designed to quantify the loss of erythromycin to kaolinite under environmentally relevant conditions. Gas Chromatography (GC) will be used to quantify erythromycin losses and to indicate any degradation products facilitated by the clay surface. These data will be used to determine binding constants between the kaolinite and erythromycin. Gas Chromatography-Mass Spectrometry (GC-MS) will be used to identify any significant degradation products. Erythromycin was purchased commercially and recrystallized under various conditions using acetone. Currently, a GC method suitable for quantifying erythromycin is being developed.

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Apr 25th, 10:00 AM Apr 25th, 12:00 PM

The Influence of Kaolinite on the Fate of Erythromycin in Soil Environments

CSU North Ballroom

This project seeks to quantify the loss of erythromycin, a common antibiotic for animals and humans, as well as identify any degradation products caused by the surface of kaolinite, a common clay mineral. Antibiotics are commonly introduced into soil environments by treatment plant effluent and agricultural runoff. The introduction of antibiotics is of particular concern because it may promote microbial resistance. Clay minerals are known to adsorb organic molecules and promote their degradation. In order to gain insight into the nature of the clay/erythromycin interactions, experiments are designed to quantify the loss of erythromycin to kaolinite under environmentally relevant conditions. Gas Chromatography (GC) will be used to quantify erythromycin losses and to indicate any degradation products facilitated by the clay surface. These data will be used to determine binding constants between the kaolinite and erythromycin. Gas Chromatography-Mass Spectrometry (GC-MS) will be used to identify any significant degradation products. Erythromycin was purchased commercially and recrystallized under various conditions using acetone. Currently, a GC method suitable for quantifying erythromycin is being developed.

Recommended Citation

Erdmann, Leila. "The Influence of Kaolinite on the Fate of Erythromycin in Soil Environments." Undergraduate Research Symposium, Mankato, MN, April 25, 2006.
https://cornerstone.lib.mnsu.edu/urs/2006/poster-session-E/8